Does it matter which slot you put an additional RAM card in?

If the RAM is the same there should be no real difference other than the fact

think of it like a bus, and each pair of ram slots gets one bus by using a 2-4 or 1-3 configuration you are giving each stick of memory

ram slot 2 and 4 1, 3, 5, 8, 28 Memory Built-in, 256GB 12GB RAM, 512GB 12GB RAM, 1TB 16GB RAM Card Slot Memory Card Slot is a special slot for inserting a memory card

rams slot receiver I build computers and the RAM should always be in the first slot on the left closest to the CPU If there is a 2nd chip it should be installed